The Spectacular Spider-Man #186 (1992)
“Funeral Arrangements Part One: Settling Scores”
Writer: J.M. DeMatteis
Artist: Sal Buscema
Vulture is going around settling scores because he has rapidly spreading cancer and wants to settle old debts before he dies. So he’s killing people who wronged him. He has some kind of score to settle with Aunt May, and shows up at her house.