Peter Parker, the Spectacular Spider-Man #065 (1982)
“The Heart is a Lonely Hunter”
Writer: Bill Mantlo
Artist: Bob Hall
Kraven again seeks to defeat Spider-Man with the help of his love Calypso. While Kraven and Spider-Man are fighting, Calypso shoots a drugged dart into Spider-Man’s ankle that causes him to hallucinate and see terrifying imagery. Kraven is upset that his defeat of Spider-Man is only due to drugs and scolds Calypso. Spider-Man jumps off the roof, still disoriented. Kraven doesn’t want Spider-Man to die like this because he wouldn’t feel honorable. He jumps off after him. A police car comes by and Kraven is arrested. Spider-Man flees and the drugs begin wearing off.