The Amazing Spider-Man #333 (1990)
Writer: David Michelinie
Artist: Erik Larsen
Venom talks with Peter at Aunt May’s and tells him to meet at the abandoned subway tunnel where he lives in 24 hours. Styx’s past is revealed. He took part in experimental drug testing and some scientist tried an unauthorized project trying to develop immunity to cancer by controlled exposure, but instead created a living cancer who can rot any organic matter by touch. Spider-Man meets Venom and Styx and Stone are close behind. Stone hits Venom with a sonic blast and Spidey goes kicks him in the face. He tries to avoid Styx’s death touch, but his fingers grow longer. Lots of fighting later and Styx eventually touches Venom and the symbiote melts off of Eddie’s body. Spider-Man webs up Styx, knocks out Stone and sends them all to jail. The symbiote is seemingly dead.