Peter Parker, the Spectacular Spider-Man #127 (1987)
“Among Us Lurks…A Lizard!”
Writer: Len Kaminsky
Artist: Alan Kupperberg
Owl kidnaps Dr. Connors’ wife and son to make him give him the formula to regrow limbs. Owl’s spine is injured and his legs don’t work. Dr. Connors’ transforms into the lizard again, but this time has control over him. He beats up (and nearly kills) street thugs to find out where his family is. Spider-Man helps him get his family back.