The Amazing Spider-Man #258 (1984)
“The Sinister Secret of Spider-Man’s New Costume!”
Writer: Tom DeFalco
Artist: Ron Frenz
Spider-Man has his suit examined by Reed Richards and discovers that it’s not some alien material, but an alien symbiote that bonds with him physically and mentally. i.e. It’s alive! Spider-Man tries to take the suit off but can’t. Richards blasts it with a sonic blast gun and it leaps off Spidey, and then they trap it in a container. Rose teams up with The Hobgoblin to take down Spider-Man and the Kingpin.