Peter Parker, the Spectacular Spider-Man #055 (1981)
“The Big Blow Out!”
Writer: Roger Stern
Artist: Luke McDonnell
A villain called Nitro (who can explode at will and reform afterwards) tries to rob a bank, but Spider-Man comes along and fights him. Spidey gets him to a chemical plant and sticks a canister of nausea gas to Nitro. When Nitro explodes and reforms, the nausea gas is part of him and makes him too sick to do anything.