The Amazing Spider-Man #214 (1981)
“Then Shall We Both Be Betrayed!”
Writer: Denny O’Neil
Artist: John Romita Jr.
Sub-Mariner hassles the Peter’s new neighbor lady, and Spider-Man saves her and fights Sub-Mariner. Sub-Mariner tries to tell Spidey that the girl is not what she seems. She’s actually an old enemy of his named Llyra in disguise as a normal woman and is the mysterious person who broke Wizard from jail and is now working with him. Wizard shoots Spider-Man and Sub-Mariner with some device as they’re fighting and some kind of great pain comes over them.