The Amazing Spider-Man #062 (1968)
“Make Way For–Medusa!”
Writer: Stan Lee
Artist: John Romita
Medusa, a woman who can control her hair like arms, is contracted by some advertisers to promote hair spray. When she refuses to make good on her promises, the advertisers tell Spider-Man she wrecked the place and she’s a menace. He fights her. They stop fighting and realize they’ve both been had. Medusa doesn’t trust humans anymore and returns to her race of non-humans underground.